Causes of anaemia in malaria

ionedTZbleTZen_USteden_USonGladheim, Kristin, Foerster, Nina Maria, .

Testing for G6PD-defekt før primakinbehandling. Prosjektoppgave, University of Oslo, en_USctABSTRACT Glucosephosphate-dehydrogenase (G6PD) deficiency is the most common enzyme deficiency worldwide, with the highest prevalence in Africa, Middle East and Southeast Asia.

When patients with G6PD deficiency are treated with primaquine due to a malaria infection caused by or P. ovale, they are in risk of developing a primaquine induced haemolytic anaemia.

Anaemia

According to WHO guidelines, patients who are in risk of having the G6PD deficiency should be screened before primaquine treatment is started. In Norway we have no such guidelines. To minimize the risk of relapsing malaria infection, the Norwegian policy has been to treat P.

vivax- and P. ovale infections with primaquine. Due to increasing immigration, the G6PD deficiency can be found in the Norwegian population. The